Aldosteronism

Aldosteronism: refractory hypertension, hypokalemia, metabolic alkalosis, aldo↓ even w salt loading, tx w eplerenone


Browse disease: Endocrine | Neuro | Renal | GI | Cardio | Respiratory | Hemonc
  • Aldosteronism
  • aka: hyperaldosteronism,
  • refractory hypertension, hypokalemia, metabolic alkalosis, aldo↓ even w salt loading, tx w eplerenone
  • refractory hypertension (unresponsive to drugs)
  • refractory hypertension, muscle weakness (hypokalemia)
  • alkalosis, metabolic alkalosis (bicarb&uarr), hypokalemia, hypomagnesia (bloodwork), aldosterone↑ even w salt loading
  • aldosterone = retain Na (hypertension), excrete K (hypokalemia), urine acidosis (blood alkalosis). Primary = low renin even w stimulation (upright posture/diuretic). Secondary = high renin even w suppression (salt loading)
  • spirinolactone, eplerenone