BOOP

BOOP: pneumonia-like (acute, cough, fever, SOB) with wt loss, but no sputum and doesn't respond to antibiotics


Browse disease: Endocrine | Neuro | Renal | GI | Cardio | Respiratory | Hemonc
  • BOOP
  • aka: Bronchiolitis obliterans organizing pneumonia, COP, cryptogenic organizing pneumonia,
  • pneumonia-like (acute, cough, fever, SOB) with wt loss, but no sputum and doesn't respond to antibiotics
  • acute onset of cough, SOB, fever, looks like pneumonia but doesn't respond to antibiotics
  • crackles, O2 sat↓
  • CXR (infiltrates, bilateral, patchy), but sputum culture is negative and don't respond to antibiotics, lavage (lymphocyte↑, PMN↑), DLCO↓, restrictive PFTs, biopsy shows fibroblast in alveoli and bronchiole
  • fibroblasts/granulation tissue plugs up alveoli and bronchiole
  • steroid