PSC

PSC: fatigue, itching, fever, AP↑ more than ALT & AST, dx w cholangiography showing bile duct strictures (beads on string), most also have UC


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  • PSC
  • aka: Primary sclerosing cholangitis,
  • fatigue, itching, fever, AP↑ more than ALT & AST, dx w cholangiography showing bile duct strictures (beads on string), most also have UC
  • fatigue, itching, fever, steatorrhea, most also have UC
  • hepatosplenomegaly, jaundice, RUQ pain
  • cholangiography shows bile duct stricturing (beads on string), colonoscopy (most also have UC), AP↑ more than other AST or ALT, IgG↑
  • endoscopy to open up stricture, antibiotic prophylaxis, liver translplant if refractory