ZES

ZES: GERD, PUD, steatorrhea, dx w fasting serum gastrin↑, secretin stimulation causes gastrin↑, tx w PPI, resection, ablation


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  • ZES
  • aka: Zollinger-Ellison syndrome, Gastrinoma,
  • GERD, PUD, steatorrhea, dx w fasting serum gastrin↑, secretin stimulation causes gastrin↑, tx w PPI, resection, ablation
  • GERD, PUD, malabsorption, steatorrhea
  • fasting serum gastrin↑, secretin stimulation (gastrinoma responds w increased gastrin secretion in contrast to normal G cells)
  • gastrin-producing tumor (most r malig) causes too much HCl production in stomach
  • PPI (omeprazole), surgery (resection, ablation)