Glitazone

Glitazone (Thiazolidinedione,): Tx: type 2 diabetes. Mech: activate PPARγ (FFA recept), inc muscle/fat insulin sensitivity, adipokine↑, GLUT↑. SE: edema, wt gain, CHF, heptox, fractures. Fact: slow onset.


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  • Glitazone
  • aka: Thiazolidinedione,
  • Tx: type 2 diabetes.
  • Mech: activate PPARγ (FFA recept), inc muscle/fat insulin sensitivity, adipokine↑, GLUT↑.
  • SE: edema, wt gain, CHF, heptox, fractures.
  • Fact: slow onset.