Sulfonamide

Sulfonamide (SMZ,): Tx: toxoplasmosis. Mech: PABA analogue = inh pteroate synthase = anti-folate = inh DNA synth. SE: blood dz (WBC↓, plt↓), kernicterus, rash, inh P450.


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  • Sulfonamide
  • aka: SMZ,
  • Tx: toxoplasmosis.
  • Mech: PABA analogue = inh pteroate synthase = anti-folate = inh DNA synth.
  • SE: blood dz (WBC↓, plt↓), kernicterus, rash, inh P450.